TABLE 1.
Case reports | Case series | Total, n/N (%) | ||||
---|---|---|---|---|---|---|
Chen et al, 13 Liu et al, 14 Li et al, 15 Fan et al, 16 Zhu et al, 17 Wang et al, 18 Chen et al, 19 Zambrano et al, 20 Wang et al, 21 Gidlöf et al, 22 Yu et al, 23 Breslin et al, 24 Iqbal et al, 25 Lee et al 26 (N = 58) | Liu et al 27 (N = 16) | Zhang et al 28 (N = 16) | Liu et al 29 (N = 15) | Chen et al 30 (N = 3) | ||
Maternal characteristics | ||||||
Age (y) (mean ± SD) | 31 ± 4 | 30 | 29 ± 3 | 32 ± 5 | 30 ± 6 | |
Gestational age in days (mean ± SD) | 253 ± 25 | N/A | 271 ± 10 | 224 ± 8 | 260 ± 14 | |
Delivery characteristics | ||||||
Total number of deliveries | 50 | 6 | 16 | 11 | 3 | 86/108 (80%) |
Patients not delivered at time of reporting of studies | 8 | 10 | 0 | 4 | 0 | 22/108 (20%) |
Delivery by cesarean section | 44 | 6 | 16 | 10 | 3 | 79/86 (92%) |
Vaginal delivery | 6 | 0 | 0 | 1 | 0 | 7/86 (8%) |
Presenting signs and symptoms | ||||||
Fever on admission | 42 | 7 | N/A | 13 | 1 | 63/92 (68%) |
Cough | 19 | 6 | 3 | 9 | 0 | 37/108 (34%) |
Malaise | 7 | 3 | 0 | 4 | 0 | 14/108 (13%) |
Dyspnea | 5 | 3 | 3 | 1 | 1 | 13/108 (12%) |
Myalgia | 8 | 0 | 0 | 3 | 0 | 11/108 (10%) |
Sore throat | 7 | 0 | 0 | 1 | 0 | 8/108 (7%) |
Diarrhea | 3 | 0 | 3 | 1 | 0 | 7/108 (6%) |
Laboratory characteristics | ||||||
Lymphocytopenia (<1 × 109/L) | 18 a | 9 | N/A | 12 | 1 | 40/68 (59%) |
Elevated C‐reactive protein concentration (mg/L) | 19 b | 13 | N/A | 10 | 3 | 45/64 (70%) |
Confirmed SARS‐CoV‐2 | 58 | 16 | 16 | 15 | 3 | 108/108 (100%) |
Other parameters | ||||||
Maternal mortality | 0 | 0 | 0 | 0 | 0 | 0/108 (0%) |
Maternal ICU admission | 3 | 0 | 0 | 0 | 0 | 3/108 (3%) |
Neonatal mortality | 1 c | 0 d | 0 | 0 f | 0 | 1/87 (1%) |
Intrauterine fetal death | 1 c | 0 d | 0 | 0 f | 0 | 1/87 (1%) |
Vertical transmission | 1 c | N/A | 0 e | 0 f | 0 | 1/75 (1%) |
N/A, data not available.
Data unavailable in 24 cases.
Data unavailable in 28 cases.
Data unavailable from 8 women still pregnant at the end of the study. One twin delivery (Gidlöf et al 22 ).
Data unavailable from 10 women still pregnant at the end of the study.
Data unavailable in 6 neonates.
Data unavailable from 4 women still pregnant at the end of the study.