TABLE 2.
Imaging Response at 3 Months After Last Cycle of Induction 177Lu-PSMA
| Response | Bone scintigraphy | Soft-tissue lesions on CT (nodal or visceral) (n = 27) | 68Ga-PSMA-11 PET | 18F-FDG PET |
| Complete response | 16 (32%) | 5 (19%) | 6 (12%) | 7 (14%) |
| Partial response | 10 (37%) | 15 (30%) | 8 (16%) | |
| Stable disease | 0 | 0 | 3 (6%) | |
| Progressive disease | 12 (24%) | 9 (33%) | 14 (28%) | 15 (30%) |
| Not performed* | 22 (44%) | 3 (11%) | 15 (30%) | 17 (34%) |
*
Because of clinical progression or death.
PET responses were assessed visually using Hicks criteria (33) and CT with RECIST 1.1 with Prostate Cancer Working Group 2 caveats; CT component of posttherapy SPECT/CT was also used for soft-tissue measurements.