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. 2020 Jun;61(6):873–880. doi: 10.2967/jnumed.119.236059

FIGURE 2.

FIGURE 2.

Representative PTEN-intact PCa lesions (A) and PTEN-loss PCa lesions (B). (A) A 63-y-old man with index tumor in peripheral zone (PSA level, 5.42 ng/mL; Gleason score, 4 + 3; maximal diameter, 1.8 cm; PTEN immunohistochemistry intact), demonstrating hypointense area on T2-weighted and ADC images and moderate uptake on PET/CT image. (B) A 67-y-old man with PCa in peripheral zone (PSA level, 5.46 ng/mL; Gleason score, 4 + 3; maximal diameter, 1.2 cm; PTEN immunohistochemistry loss), showing hypointense area on T2-weighted and ADC images and strong uptake on PET/CT image. Lesions are outlined. HE = hematoxylin and eosin; IHC = immunohistochemistry; T2WI = T2-weighted image.