TABLE 3.

Diagnostic Accuracies of Different Imaging Parameters for Detection of PTEN Status

Variable	AUC	Cutoff	Sensitivity	Specificity
Per-patient analysis
ADCmean (μm2/s)	0.56 (0.29–0.84)	577	0.78	0.56
PI-RADS score (3/4/5)	0.58 (0.47–0.70)	4	0.62	0.56
Maximum diameter (cm)	0.62 (0.46–0.79)	1.25	0.73	0.56
SUVmax	0.84 (0.73–0.94)	10.3	0.80	0.77
Per-lesion analysis
ADCmean (μm2/s)	0.53 (0.25–0.82)	577	0.75	0.58
PI-RADS score (3/4/5)	0.62 (0.50–0.75)	4	0.59	0.58
Maximum diameter (cm)	0.68 (0.55–0.81)	1.25	0.78	0.53
SUVmax	0.88 (0.91–0.95)	10.3	0.83	0.74

AUC = area under curve; PI-RADS: Prostate Imaging Reporting and Data System; maximum diameter = maximum diameter of lesion on MRI.

Data in parentheses are 95% CIs.