Table 1.
Screening of specific mAb clones against MERS CoV cHA stalk (IAV and IBV)
| Immunized antigen | Sequences of target antigen (strain) | Number of positive clones using ELISA (coating antigen) | Efficiency of positive mAb screening | ||
|---|---|---|---|---|---|
| mRID‐RBD | mRID | Both | Specific mAbs against target antigen (including all clones) | ||
| mRID‐RBD (MERS‐CoV) | Human betacoronavirus 2c EMC/2012 | 97 | 4 | 38 | 96% (69.8%) |
| mRID‐cHA stalk (IAV) | High frequency fragments of subtype H1, H2, H5, H9 | 15 | 0 | ND | 100% |
| mRID‐cHA stalk (IBV) | Consensus HA stalk sequences of 6 IBV | 13 | 0 | 1 | 100% (92.85%) |