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. 2020 May 25;14:523. doi: 10.3389/fnins.2020.00523

TABLE 7.

Pearson product-moment correlations between cognitive performance-relevant parameters and vagally mediated heart rate variable parameters during the single stimulation phase (tVNS) and the task phase (task) for active and sham conditions. Coefficients for the cognitive flexibility tasks.

Active Stimulation
Sham Stimulation
RT
Percentage error
RT
Percentage error
Non-switch trials Switch trials Non-switch trials Switch trials Switch costs Non-switch trials Switch trials Non-switch trials Switch trials Switch costs
NLT
RMSSD tVNS Pearson’s r –0.28 –0.24 0.40* 0.14 0.13 0.12 0.15 0.19 –0.06 –0.02
p-value 0.132 0.179 0.025 0.434 0.434 0.513 0.430 0.308 0.727 0.934
Task Pearson’s r –0.06 –0.03 0.33 0.31 0.13 0.10 0.29 0.22 –0.02 0.28
p-value 0.732 0.860 0.070 0.081 0.475 0.595 0.113 0.238 0.909 0.115
HF tVNS Pearson’s r −0.44* −0.50** 0.37* 0.31 0.14 0.09 –0.10 0.11 –0.23 –0.28
p-value 0.015 0.005 0.046 0.099 0.463 0.677 0.626 0.599 0.279 0.170
Task Pearson’s r −0.39* –0.24 0.28 0.22 0.42* –0.10 –0.02 0.48* 0.07 0.15
p-value 0.034 0.204 0.129 0.242 0.020 0.621 0.914 0.015 0.748 0.482
DCCS
RMSSD tVNS Pearson’s r –0.27 –0.17 0.24 0.29 0.40* 0.09 0.04 –0.03 –0.01 –0.10
p-value 0.134 0.351 0.180 0.103 0.024 0.623 0.837 0.869 0.973 0.603
Task Pearson’s r –0.25 –0.14 0.16 0.23 0.37* 0.06 0.01 0.03 0.02 –0.08
p-value 0.177 0.440 0.385 0.212 0.035 0.741 0.953 0.858 0.920 0.660
HF tVNS Pearson’s r −0.40* −0.42* 0.29 0.31 –0.08 0.05 0.04 –0.19 –0.14 0.03
p-value 0.026 0.018 0.110 0.089 0.684 0.796 0.835 0.356 0.483 0.900
Task Pearson’s r 0.07 –0.01 –0.27 –0.19 −0.42* –0.05 –0.03 0.02 –0.06 0.10
p-value 0.715 0.970 0.150 0.314 0.019 0.819 0.905 0.931 0.761 0.619

*p < 0.05, **p < 0.01. Non-adjusted p values. RT = reaction times; RMSSD = root mean square of successive differences; HF = high frequency; NLT = Number Letter task; DCCS = Dimensional Change Card Sorting task; tVNS = transcutaneous vagus nerve stimulation (single stimulation phase).