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. 2020 Apr 13;8:136–142. doi: 10.1016/j.ibror.2020.04.001

Table 3.

Correlation between CSF markers and symptom severity or cognitive functions in FEP patients.

SNAP-25tot SNAP-25aa40 SYT-1
PANSS
PANSS positive symptoms 0.289 0.179 0.261
PANSS negative symptomsa 0.264 0.276 0.127
PANSS general symptoms 0.268 0.159 0.206
PANSS total 0.292 0.198 0.222



Severity of illness
GAF symptoma −0.087 −0.131 −0.139
GAF functioning −0.157 −0.064 −0.154
CGIa 0.111 0.226 0.195



Cognitive test*
TMTa 0.066 −0.109 −0.102
BACS_SC −0.011 0.052 0.014
HVLT_R −0.125 −0.071 −0.055
WMS_II_SS −0.080 −0.147 −0.111
LNS −0.175 −0.012 −0.020
NAB_MAZESa 0.026 0.018 0.021
BVMT_R 0.020 0.001 0.008
Fluency 0.091 −0.015 0.032
MSCEIT_ME −0.040 −0.047 −0.066
CPT_IP −0.022 0.075 −0.023
*

Bonferroni correction was used in the Cognitive test, giving an α-threshold of *P < 0.005 (0.05/10).

a

Spearman correlation otherwise Pearson’s correlation applied, results represented the r value. Abbreviations: BACS-SC, Brief Assessment of Cognition in Schizophrenia Symbol Coding; BVMT-R, Brief Visuospatial Memory Test-Revised; CGI, Clinical Global Impression; CPT-IP, Continuous Performance Test-Identical Pairs; GAF, Global Assessment of Functioning; HVLT-R, Hopkins Verbal Learning Test-Revised; PANSS, Positive and Negative Syndrome Scale; TMT, Trail Making Test; WMS-III, Wechsler Memory Scale-3rd Edition.