TABLE 3.

Analytical performance characteristics of the LRRK2 SISCAPA assay using recombinant LRRK2 and an endogenous QC (EQC) CSF sample.

Type	STD	LQC	STD	STD	MQC	STD	STD	HQC	STD	EQC
Pg/ml	5	7.5	10	20	40	50	100	150	200
Cal1	7.51	9.08	10.09	18.86	32.61	49.73	97.40	154.30	201.41
Cal2	5.30	9.59	11.10	18.16	31.92	50.40	100.04	184.09	209.08
Cal3	5.43	6.36	7.54	19.08	36.54	53.18	100.73	142.80	199.04	15.54
Cal4		11.12	9.90	17.20	33.21	44.42	102.87	157.01	200.11	17.77
Cal5	4.28	7.93	9.14	18.91	40.26	51.19	103.24	148.47	198.26	16.53
Cal6	8.17	8.61	11.45	17.55	35.05	47.80	98.76	138.01	201.26	20.05
average	6.14	8.78	9.87	18.29	34.93	49.45	100.51	154.12	201.53	17.47
stdev	1.63	1.60	1.42	0.79	3.11	3.03	2.28	16.29	3.90	1.94
CV%	26.62	18.22	14.37	4.29	8.91	6.13	2.27	10.57	1.93	11.12
Bias%	22.71	17.08	−1.30	−8.54	−12.67	−1.09	0.51	2.74	0.76