Table I.
Characteristic of Spanish and Italian cohorts
| Characteristics | Spain, n = 132 | Italy, n = 100 |
|---|---|---|
| Age, mean (range) | 19.9 (1-56 y) | 12.9 (3 mo-17 y) |
| Male sex (%) | 71 (53.8) | 64 (64) |
| Cutaneous symptoms (pain, itching, burning, swelling, erythema) (%) | NA | 61 (61) |
| COVID-19 symptoms (%) | 18 (13.6) | 16 (16) |
| COVID-19–positive cases (%) | 2 (1.5) | 1 (1) |
| Location of skin lesions (%) | Hands: 41 (31) Feet: 108 (81.8) |
Hands: 25 (25) Feet: 75 (75) |
| Duration of skin lesions, mean (range), d | 8.7 (2-24) | Improvement at day 12 = 76% |
| Therapy (%) | 74 (74) | |
| Topical steroids | 40 | |
| Topical antibiotics | 8 | |
| Topical heparin | 9 | |
| Topical antifungal | 4 | |
| Systemic antibiotics | NA | 2 |
| Systemic steroids | 4 | |
| Antihistamines | 4 | |
| Paracetamol | 6 | |
| Gentamicin + betamethasone | 11 | |
| No therapy | 26 (26) | |
| Improvement by day 4 (%) | ||
| Therapy | 31 (41.9) | |
| No therapy | 13 (49.9) | |
| Improvement by day 8 (%) | ||
| Therapy | 43 (58.1) | |
| No therapy | 19 (73.1) | |
| Improvement by day 12 (%) | ||
| Therapy | 55 (74.3) | |
| No therapy | 21 (80.7) |
COVID-19, Coronavirus disease 2019; NA, not applicable.