TABLE 4.
Characteristics (1996 to 1998) of Patients by Incident HF Subtype (ARIC, 2005 to 2015)
| No HF (n = 6,583) | Any HF (n = 1,005) | HFpEF (n = 278) | HFrEF (n = 275) | HF Type (n = 452) | |
|---|---|---|---|---|---|
| Age, yrs | 61.6 ± 5.0 | 64.2 ± 5.0 | 64.5 ± 5.4 | 64.4 ± 5.5 | 64.0 ± 5.4 |
| Men | 2,693 (41) | 447 (44) | 87 (31) | 170 (62) | 190 (42) |
| Black | 1,397 (21) | 283 (28) | 80 (29) | 76 (28) | 127 (28) |
| Education high school or less | 1,015 (15) | 276 (27) | 80 (29) | 84 (31) | 112 (25) |
| BMI, kg/m2 | 28.4 ± 5.0 | 29.7 ± 6.0 | 30.2 ± 7.0 | 28.9 ± 5.0 | 29.8 ± 6.0 |
| Hypertension | 2,662 (40) | 600 (60) | 168 (60) | 164 (60) | 268 (59) |
| Diabetes | 779 (12) | 260 (26) | 79 (28) | 76 (28) | 105 (23) |
| Total cholesterol, mg/dl | 202.3 ± 36.0 | 200.7 ± 38.0 | 205.5 ± 40.0 | 195.0 ± 36.0 | 201.3 ± 38.0 |
| Hyperlipidemia* | 3,713 (56) | 573 (57) | 177 (64) | 140 (51) | 256 (57) |
| Ever smoker | 3,586 (54) | 659 (66) | 172 (62) | 190 (69) | 297 (66) |
| eGFR, ml/min/1.73 m2 | 88.4 ± 15.0 | 83.6 ± 18.0 | 82.9 ± 18.0 | 83.2 ± 19.0 | 84.4 ± 18.0 |
| CKD | 247 (4) | 91 (9) | 21 (8) | 31 (11) | 39(9) |
| Aspirin use | 3,566 (54) | 591 (59) | 158 (57) | 154 (56) | 279 (62) |
| Prevalent coronary heart disease | 278 (4) | 120 (12) | 20 (7) | 48 (17) | 52 (12) |
| Prevalent stroke | 71 (1) | 33 (3) | 10 (4) | 8 (3) | 15 (3) |
| Prevalent atrial fibrillation | 166 (3) | 86 (9) | 30 (11) | 21 (8) | 35 (8) |
| History of claudication | 196 (3) | 62 (6) | 16 (6) | 19(7) | 27 (6) |
Values are mean ± SD or n (%).
*
Total cholesterol ≥200 mg/dl or use of lipid medications.
HFpEF = HF with preserved ejection fraction; HFrEF = HF with reduced ejection fraction; other abbreviations as in Table 1.