TABLE 5.
Crude Incidence and Adjusted Risk for VTE bv Incident HF Subtype (ARIC, 2005 to 2015)
| No HF (n = 6,583) | Any HF (n = 1,005) | HFpEF (n = 278) | HFrEF (n = 275) | Undetermined HF Type (n = 452) | |
|---|---|---|---|---|---|
| Number of VTE events | 199 | 63 | 21 | 19 | 23 |
| Person-years | 65,451 | 2,895 | 908 | 778 | 1,208 |
| Incidence rate (95% CI)* | 3.04 (2.64–3.49) | 21.8 (16.9–27.6) | 23.1 (14.7–34.7) | 24.4 (15.2–37.4) | 19.0 (12.4–28.1) |
| Hazard ratio (95% CI) | 1.00 (reference) | 5.15 (3.80–6.98) | 4.71 (2.94–7.52) | 5.53 (3.42–8.94) | 4.09 (2.60–6.44) |
| Race interaction, p value | 0.36 | 0.49 | 0.86 | 0.55 | |
| Number of PE events | 135 | 36 | 12 | 7 | 17 |
| Hazard ratio (95% CI) | 1.00 (reference) | 4.41 (2.98–6.54) | 4.09 (2.22–7.55) | 3.12 (1.45–6.74) | 4.55 (2.67–7.75) |
| Number of DVT events | 64 | 27 | 9 | 12 | 6 |
| Hazard ratio (95% CI) | 1.00 (reference) | 6.66 (4.11–10.81) | 5.91 (2.84–12.3) | 10.1 (5.34–19.0) | 3.21 (1.34–7.66) |
| Number of unprovoked VTE events | 87 | 26 | 8 | 7 | 11 |
| Hazard ratio (95% CI) | 1.00 (reference) | 4.77 (2.99–7.62) | 4.01 (1.89–8.50) | 4.66 (2.13–10.2) | 4.59 (2.37–8.90) |
| Number of provoked VTE events | 112 | 37 | 13 | 12 | 12 |
| Hazard ratio (95% CI) | 1.00 (reference) | 5.53 (3.71–8.25) | 5.39 (2.95–9.82) | 6.44 (3.49–11.9) | 3.74 (2.00–7.00) |