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. 2020 Jun 10;322:177–186. doi: 10.1016/j.jconrel.2020.03.026

Fig. 1.

Fig. 1

Schematic representation of the mechanism of action of a ESK-containing MN patch. ESK-containing MN patches consist of hydrogel-forming MN arrays and ESK-containing reservoir. Hydrogel-forming MN arrays take up skin interstitial fluid, inducing diffusion of ESK from an ESK-containing reservoir through the swollen micro-projections.