Table 4.
Percentage of participants with blood values above or below accepted norms or the presence of H. pylori infection by group.
| Variable |
Group A |
Group B |
||||
|---|---|---|---|---|---|---|
| Threshold used for status | Cases n = 24 | Controls n = 24 | p | Cases n = 38 | Controls n = 38 | p |
| TALP (%) High: ≥300 U/mL | 92 | 17 | ≤0.0001 | 42 | 16 | 0.01 |
| TALP (%) Severe: ≥960 U/mL | 8 | 0 | 0.2 | 0 | 0 | – |
| PTH (%) High: >58 ng/L | 88 | 25 | ≤0.0001 | 42 | 26 | 0.2 |
| 25OHD (%) Low: <25 nmol/L | 63 | 8 | ≤0.0001 | 13 | 5 | 0.2 |
| 25OHD (%) Severe <12.5 nmol/L | 4 | 0 | 0.3 | 0 | 0 | – |
| pCa (%) Low: ≤2.25 mmol/L | 91 | 88 | 0.9 | 72 | 75 | 0.6 |
| pPhos (%) Low: ≤1.45 or ≤1.20 mmol/La | 83 | 22 | ≤0.0001 | 16 | 14 | 0.8 |
| iFGF23 (%) Low: <5 pg/mL | 88 | 4 | ≤0.0001 | 21 | 0 | 0.006 |
| iFGF23 (%) High: ≥51.9 pg/mL | 0 | 0 | – | 0 | 0 | – |
| cFGF23 (%) High: >125 RU/mL | 4 | 8 | 0.6 | 8 | 3 | 0.3 |
| Hb (%) Low: <110 or <115 g/La | 67 | 71 | 0.8 | 76 | 74 | 0.8 |
| Ferritin (%) Low: ≤10 or ≤15 μg/La | 4 | 8 | 0.6 | 5 | 8 | 0.6 |
| CRP (%) High: ≥5 mg/L | 15 | 7 | 0.5 | 11 | 5 | 0.4 |
| Iron deficiency anaemia (%) | 8 | 17 | 0.4 | 18 | 21 | 0.8 |
| H. pylori infected (%) | 29 | 58 | 0.04 | 49 | 51 | 0.5 |
Group A: active rickets, Group B: rickets-like bone deformities. McNemar ϰ2 test p-values are presented. aThreshold values for <5 and >5 year old children. TALP: Total alkaline phosphatase, PTH: Parathyroid hormone, 25OHD: 25-hydroxyvitamin D, pCa: Calcium; pPhos: Phosphate, iFGF23 and cFGF23: intact- and c-terminal fibroblast growth factor, Hb: Haemoglobin, sTfR: Serum transferrin receptor, CRP: C-reactive protein, Iron Deficiency Anaemia: Low haemoglobin plus microcytic and hypochromic red blood cells.