Skip to main content
. 2020 Jul;136:115367. doi: 10.1016/j.bone.2020.115367

Table 1.

Cortical architecture and geometry of Dp1Tyb and control male and female mice at 6 and 16 weeks.

Male control
6 weeks
Male Dp1Tyb
6 weeks
Female control
6 weeks
Female Dp1Tyb
6 weeks
Between subjects effects
Interaction
Between subjects effects
Genotype
Between subjects effects
Sex
n = 10 n = 10 n = 12 n = 10
Cortical area (mm2) 0.82 (0.03)a 0.58 (0.02)b 0.71 (0.03)c 0.56 (0.02)b p = 0.091
p2 = 0.074]
p < 0.001
p2 = 0.566]
p = 0.026
p2 = 0.124]
Cortical thickness (mm) 0.19 (0.005)a 0.15 (0.003)b 0.17 (0.008)a,b 0.15 (0.007)b p = 0.270
p2 = 0.032]
p < 0.001
p2 = 0.367]
p = 0.139
p2 = 0.057]
Imax (mm4) 0.27 (0.01)a 0.16 (0.01)b 0.22 (0.01)c 0.15 (0.01)b p = 0.075
p2 = 0.081]
p < 0.001
p2 = 0.585]
p = 0.019
p2 = 0.137]
Imin (mm4) 0.15 (0.01)a 0.08 (0.004)b 0.12 (0.005)c 0.08 (0.003)b p = 0.004
p2 = 0.202]
p < 0.001
p2 = 0.740]
p = 0.001
p2 = 0.253]
TMD (g/cm3 HA) 1.05 (0.01)a 0.99 (0.01)b 1.05 (0.02)a 1.01 (0.02)a,b p = 0.655
p2 = 0.005]
p = 0.001
p2 = 0.253]
p = 0.592
p2 = 0.008]



Male control
16 weeks
Male Dp1Tyb
16 weeks
Female control
16 weeks
Female Dp1Tyb
16 weeks
Between subjects effects
Interaction
Between subjects effects
Genotype
Between subjects effects
Sex
n = 13 n = 12 n = 20 n = 22
Cortical area (mm2) 1.09 (0.02)e 0.92 (0.02)f 0.89 (0.01)f 0.82 (0.01)g p = 0.005
p2 = 0.130]
p < 0.001
p2 = 0.476]
p < 0.001
p2 = 0.585]
Cortical thickness (mm) 0.24 (0.003)e 0.24 (0.004)e 0.22 (0.002)f 0.22 (0.002)f p = 0.184
p2 = 0.0.30]
p = 0.136
p2 = 0.038]
p < 0.001
p2 = 0.341]
Imax (mm4) 0.43 (0.02)e 0.29 (0.02)f 0.26 (0.01)f 0.21 (0.01)g p = 0.001
p2 = 0.189]
p < 0.001
p2 = 0.543]
p < 0.001
p2 = 0.681]
Imin (mm4) 0.20 (0.01)e 0.12 (0.005)f,g 0.13 (0.004)f 0.11 (0.004)g p < 0.001
p2 = 0.241]
p < 0.001
p2 = 0.609]
p < 0.001
p2 = 0.452]
TMD (g/cm3 HA) 1.14 (0.02) 1.14 (0.03) 1.15 (0.02) 1.17 (0.02) p = 0.733
p2 = 0.002]
p = 0.889
p2 = 0.000]
p = 0.573
p2 = 0.006]

Values are averages (SEM). Similarities and differences between individual groups as determined from Tukey's multiple comparisons post hoc tests; values with the same superscript letter are not significantly different. Letters a,b,c,d are used for comparisons of 6 week old animals; letters e,f,g,h are used for comparisons of 16 week old animals. Data without letters within a single row are not significantly different from each other. Subject effects are p values and partial eta squared (ηp2) in brackets.