Table 1.

Summary of Demographic and Laboratory Data for HIV-1-Infected Cohorts from Nigeria and Malawi

	Gender	On therapy	CD4 cells/μL of blood	HIV RNA copies/mL	HIV RNA copies/mL	Next-generation sequences generated		SGA sequences generated		CM antigen in CSF	CM confirmation method
				Plasma	CSF	Plasma	CSF	Plasma	CSF
A02	Male	Yes	311	27,456	3,656	47	55	29	26	No	CrAg test
A03	Female	Yes	251	320	320	—	—	—	—	No	CrAg test
A04	Female	Yes	51	162,544	2,104	33	120	24	15	No	CrAg test
A05	Female	Yes	125	5,648	4,608	33	327	2	22	No	CrAg test
A06	Female	Yes	355	320	320	—	—	—	—	No	CrAg test
A07	Male	Yes	245	320	320	—	—	—	—	No	CrAg test
A08	Male	No	NA	3,235,600	720	779	0	—	—	No	CrAg test
A09	Female	Yes	84	320	320	—	—	—	—	No	CrAg test
A10	Female	Yes	349	439,512	554,088	883	2,320	19	41	No	CrAg test
A11	Female	Yes	406	320	320	—	—	—	—	No	CrAg test
A13	Male	Yes	130	1,073,000	5,107,488	334	35,114	38	36	No	CrAg test
A01	Male	Yes	17	122,088	320	110	—	—	—	Yes	CrAg test
A12	Male	Yes	16	11,480	6,344	192	969	6	18	Yes	CrAg test
ACTA3153	Female	Yes	9	10,048	1,368	—	—	ND	ND	Yes	Culture
ACTA3154	Male	Yes	9	320	320	—	—	ND	ND	Yes	Culture
ACTA3155	Male	Yes	294	320	320	—	—	ND	ND	Yes	Culture
ACTA3156	Female	No	32	35,528	320	—	—	ND	ND	Yes	Culture
ACTA3157	Male	No	15	94,392	320	—	—	ND	ND	Yes	Culture
ACTA3159	Male	No	43	680,442	14,640	905	—	ND	ND	Yes	Culture
ACTA3160	Male	Yes	5	7,976	320	—	—	ND	ND	Yes	Culture
ACTA3162	Male	Yes	35	70,408	320	97	—	ND	ND	Yes	Culture
ACTA3163	Female	No	18	157,120	320	41	—	ND	ND	Yes	Culture
ACTA3164	Male	Yes	26	320	1,328	—	—	ND	ND	Yes	Culture
ACTA3165	Female	Yes	3	20,616	320	4	—	ND	ND	Yes	Culture
ACTA3166	Female	No	7	181,920	1,008	75	—	ND	ND	Yes	Culture
ACTA3167	Male	Yes	65	320	320	—	—	ND	ND	Yes	Culture
ACTA3168	Female	Yes	121	320	520	—	—	ND	ND	Yes	Culture
ACTA3169	Female	Yes	44	320	4,224	—	—	ND	ND	Yes	Culture
ACTA3170	Male	Yes	19	43,496	10,184	596	—	ND	ND	Yes	Culture
ACTA3171	Male	No	28	521,920	43,200	109	5	ND	ND	Yes	Culture
ACTA3172	Female	Yes	48	11,072	1,672	—	—	ND	ND	Yes	Culture
ACTA3173	Male	Yes	2	57,512	11,312	6	1	ND	ND	Yes	Culture
ACTA3174	Male	Yes	174	400	320	1	—	ND	ND	Yes	Culture
ACTA3175	Female	Yes	6	45,670	43,583	93	4	ND	ND	Yes	Culture
ACTA3176	Male	Yes	255	320	320	—	—	ND	ND	Yes	Culture
ACTA3177	Male	Yes	294	460	320	3	—	ND	ND	Yes	Culture
ACTA3178	Female	No	40	22,410	4,387	63	15	ND	ND	Yes	Culture
ACTA3179	Female	No	31	31,612	27,492	1,245	589	ND	ND	Yes	Culture
ACTA3180	Female	Yes	154	320	320	—	—	ND	ND	Yes	Culture
ACTA3181	Male	Yes	189	356	2,563	19	64	ND	ND	Yes	Culture
ACTA3182	Female	No	2	2,198	854	496	693	ND	ND	Yes	Culture
ACTA3183	Male	Yes	72	7,146	1,656	526	49	ND	ND	Yes	Culture
ACTA3184	Female	Yes	85	320	320	—	—	ND	ND	Yes	Culture
ACTA3185	Male	No	26	79,432	12,495	787	6,416	ND	ND	Yes	Culture
ACTA3186	Male	Yes	5	356	320	35	3	ND	ND	Yes	Culture

ACTA, Advancing Cryptococcal meningitis Treatment for Africa; CM, cryptococcal meningitis; CSF, cerebrospinal fluid; HIV, human immunodeficiency virus; ND, not done; SGA, single-genome amplification.