Table 1.
| Substantial HIV risk | Sexual partner with HIV |
| Recent bacterial STD | |
| High number of sex partners | |
| History of inconsistent or no condom use | |
| Commercial sex work | |
| Lives in high-prevalence area or network | |
| Clinical eligibility | Documented negative HIV test before prescribing PrEP |
| No signs/symptoms of acute HIV infection | |
| Normal renal function, no contraindicated medications | |
| Documented hepatitis B virus infection and vaccination status |
PrEP, pre-exposure prophylaxis.