Table 2.
Results of serum analysis after 12 weeks of RHEC administration to OVX rats.
| Group | Sham | OVX | OVX | ||
|---|---|---|---|---|---|
| RHEC (125) | RHEC (250) | RHEC (500) | |||
| ALT (U/L) | 35.8 ± 10.6 | 37.0 ± 2.5 | 38.8 ± 5.9 | 36.9 ± 4.1 | 35.3 ± 2.9 |
| AST (U/L) | 72.5 ± 17.1 | 78.0 ± 5.6 | 85.9 ± 8.3 | 79.0 ± 8.3 | 72.9 ± 4.9 |
| T-Chol (mg/dL) | 76.0 ± 14.7c | 123.7 ± 17.6 | 117.1 ± 14.1 | 109.6 ± 9.0 | 93.6 ± 10.4c |
| TG (mg/dL) | 69.1 ± 16.4 | 100.4 ± 38.7 | 78.0 ± 23.8 | 73.1 ± 10.2 | 65.7 ± 14.5 |
| HDL-C (mg/dL) | 58.5 ± 10.6a | 73.0 ± 6.1 | 81.2 ± 8.8 | 79.4 ± 6.3 | 67.7 ± 7.4 |
| LDL-C (mg/dL) | 6.8 ± 109c | 13.0 ± 1.8 | 15.2 ± 2.4 | 13.6 ± 1.2 | 11.4 ± 1.1 |
| ALP (U/L) | 41.1 ± 10.6c | 69.7 ± 9.8 | 74.0 ± 17.6 | 58.1 ± 11.2 | 52.9 ± 5.1 |
| Osteocalcin (pg/ml) | 771.4 ± 322.9b | 1723.3 ± 153.6 | 1743.3 ± 425.5 | 1498.1 ± 267.8 | 1265.1 ± 127.9 |
| CTX-1 (pg/ml) | 7.15 ± 1.64c | 15.40 ± 3.90 | 11.81 ± 2.63a | 11.53 ± 1.30b | 6.48 ± 2.02c |
| SOD (U/ml) | 42.625 ± 12.856a | 17.423 ± 14.266 | 37.263 ± 22.755 | 46.711 ± 11.368a | 48.704 ± 14.952b |
| MDA (µM/ml) | 10.24 ± 3.45b | 19.22 ± 3.86 | 14.65 ± 5.19 | 13.74 ± 3.50 | 11.54 ± 4.61a |
Values are expressed as mean ± SD (n = 7). OVX, ovariectomy; RHEC, combination of red clover extract and hops extract. aP < 0.05 versus OVX; bP < 0.01 versus OVX; cP < 0.001 versus OVX.