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. 2020 May 31;2020:3012198. doi: 10.1155/2020/3012198

Table 4.

Percentages of protection in curcumin and Cur-CS nanoparticle treatments with virus in different exposure methods at different concentrations.

Compound Concentration (μM) Pretreatment Cotreatment Posttreatment
48 h 72 h 48 h 72 h 48 h 72 h
Curcumin 2.5 0.00 ± 0.00a 0.58 ± 1.00a 12.34 ± 2.23a 5.76 ± 4.13a 0.85 ± 1.35a 0.05 ± 0.08a
5 0.38 ± 0.66a 1.74 ± 1.06ab 21.98 ± 7.01b 11.99 ± 3.43b 0.08 ± 0.13a 0.99 ± 1.71a
10 3.87 ± 1.64ab 1.16 ± 1.82a 40.08 ± 3.71d 18.82 ± 1.93c 13.31 ± 3.93b 2.59 ± 1.55a
20 12.79 ± 2.27c 5.12 ± 2.03bc 55.95 ± 1.82e 22.25 ± 2.05c 17.28 ± 0.78bc 2.13 ± 1.91a
Cur-CS nanoparticles 2.5 0.98 ± 1.70a 0.89 ± 1.30a 11.52 ± 2.93a 6.29 ± 4.28a 0.34 ± 0.59a 0.42 ± 0.73a
5 6.53 ± 4.46b 1.30 ± 2.26ab 32.51 ± 3.53c 12.23 ± 3.03b 3.87 ± 3.34a 1.12 ± 1.01a
10 14.43 ± 6.27c 7.98 ± 3.93c 49.37 ± 2.95e 21.18 ± 1.91c 18.02 ± 2.21c 3.06 ± 1.00a
20 20.12 ± 3.71d 11.67 ± 1.76d 67.88 ± 4.08f 28.43 ± 3.92d 31.25 ± 3.19d 12.24 ± 4.46b

Data are presented as mean ± SD (n = 3) and analysed using one-way ANOVA and post hoc Duncan multiple test. For each time interval, means within a column with different roman letters were significantly different (p < 0.05) from each other. Cur-CS: curcumin-encapsulated chitosan.