Table 7.
Measurement of immune-related protein concentrations (pg/mL) of different treatment groups in infected cells at 24 h.
| Cytokine/chemokine | Uninfected control cells | Infected cells | Infected cells treated with curcumin | Infected cells treated with Cur-CS nanoparticles |
|---|---|---|---|---|
| PDGF-BB | 350.4 ± 7.7a | 445.6 ± 18.7b | 446.0 ± 0.0b | 439.3 ± 0.0b |
| IL-8 | 222.4 ± 18.7a | 2078.0 ± 138.6d | 1509.5 ± 16.3c | 1153.0 ± 2.8b |
| KC | 17.26 ± 12.84a | 80.76 ± 3.71c | 58.52 ± 15.92bc | 46.15 ± 1.58b |
| SDF-1 | 76.3 ± 0.0a | 161.3 ± 7.1b | 163.5 ± 3.1b | 155.3 ± 4.1b |
| RANTES | 15.9 ± 6.5a | 868.6 ± 62.1d | 746.7 ± 18.3c | 647.6 ± 29.9b |
| MCP-1 | 735.5 ± 34.2a | 934.8 ± 0.0c | 934.8 ± 0.0c | 893.3 ± 0.0bc |
| TNFα | 26.97 ± 1.07a | 38.13 ± 0.00b | 37.40 ± 1.04b | 35.18 ± 2.09b |
| IL-18 | <31.53 | 60.62 ± 3.50c | 47.92 ± 1.73ab | 42.68 ± 1.13a |
Data are presented as mean ± SD where each experiment was performed in duplicate and analysed using one-way ANOVA and post hoc Duncan multiple test. For each cytokine/chemokine, means within a row with different roman letters were significantly different (p < 0.05) from each other. Cur-CS: curcumin-encapsulated chitosan.