Table 8.
Cytokine/chemokine | Uninfected control cells | Infected cells | Infected cells treated with curcumin | Infected cells treated with Cur-CS nanoparticles |
---|---|---|---|---|
PDGF-BB | 326.8 ± 8.81a | 440.5 ± 43.1b | 354.2 ± 30.0a | 350.0 ± 7.7a |
IL-6 | <37.42 | 108.06 ± 4.85 | 54.75 ± 6.34∗ | <39.42 |
IL-8 | 423.3 ± 18.5a | 1660.0 ± 196.6c | 1074.5 ± 9.2b | 641.0 ± 28.4a |
KC | 21.0 ± 7.5a | 266.1 ± 35.2d | 186.4 ± 14.2c | 68.0 ± 0.0b |
SDF-1 | 69.1 ± 10.2a | 158.2 ± 0.9b | 84.2 ± 2.9a | 69.9 ± 11.4a |
RANTES | 24.2 ± 5.3a | 2317.0 ± 355.0c | 618.6 ± 70.8b | 501.1 ± 69.1b |
MCP-1 | 711.4 ± 0.0a | 934.2 ± 57.9b | 735.5 ± 34.2a | 686.0 ± 35.8a |
TNFα | 27.72 ± 0.00a | 46.83 ± 6.11b | 35.18 ± 2.09a | 26.97 ± 1.07a |
Data are presented as mean ± SD where each experiment was performed in duplicate and analysed using one-way ANOVA and post hoc Duncan multiple test. For each cytokine/chemokine, means within a row with different roman letters were significantly different (p < 0.05) from each other. Mean with an asterisk (∗) was significantly (p < 0.05) different from the positive control (infected cells). Cur-CS: curcumin-encapsulated chitosan.