Table 5.
Comparison of vascular endothelial function between the two groups before and after treatment
| Ligliptin treatment group | Gliquidone treatment group | P value | |
| Number of cases | 54 | 56 | |
| FMD (%) | |||
| Before treatment | 6.33 (1.21) | 6.40 (1.16) | 0.757 |
| After treatment | 7.98 (1.22)a | 7.10 (1.13)a | 0.000 |
| PAI-1 (ng/mL) | |||
| Before treatment | 2.45 (0.43) | 2.51 (0.40) | 0.450 |
| After treatment | 2.03 (0.56)a | 2.06 (0.61)a | 0.789 |
| NO (μmol/L) | |||
| Before treatment | 154.42 (32.19) | 150.03 (30.03) | 0.461 |
| After treatment | 190.78 (30.32)a | 168.20 (29.37)a | 0.000 |
a
P < 0.05 vs before treatment. FMD: Endothelin-dependent diastolic function; PAI-1: Plasminogen activator inhibitor-1; NO: Nitric oxide.