Fig. 1.

Improvement in IRMA with anti-VEGF treatment (Regressed IRMAs). The upper row demonstrates foci of IRMAs (arrows) prior to intervention and the lower row demonstrates improvement of the same IRMA foci after anti-VEGF injection. Note that IRMA branches become incorporated into the surrounding capillary bed with a decrease in convolution of vessels to form a more normal branching pattern. There is also a reduction in the surrounding adjacent area of non-perfusion. Improvement may be partial (red and green arrows) or very marked (yellow and purple arrows)