| Patients | PPV3 (rate of malignancy among cases with positive results on screening who underwent biopsy) |
| Inclusion criteria | |
| Women with a personal history of breast cancer and had undergone curative-intent treatment | Sensitivity (TP/[TP + FP]) |
| Specificity (TN/[TN + FN]) | |
| Exclusion criteria | Number of screens needed to detect on cancer |
| Pregnant, lactating, or known metastatic disease | Recall rate (proportion of women with a positive screen result) |
| Non-human research participants | Emotional impact (e.g., anxiety, depression) of positive results (true- and false-positive findings) |
| Male study participants | |
| Interventions | Exclusion criteria |
| Inclusion criteria | Outcomes not listed |
| Magnetic resonance imaging | Economic outcomes only |
| Mammography | Timing |
| CBE | Inclusion criteria |
| No screening | Articles published after 2000 |
| Ultrasound | Studies of any duration |
| Exclusion criteria | Settings |
| Screening modalities that do not include MRI as a study group | Inclusion criteria |
| MRI for any purpose other than screening (i.e., diagnostic) | Any setting where MRI breast cancer screening is provided |
| Comparators | Study Design |
| Inclusion criteria | Inclusion criteria |
| MRI vs. Mammography (plus Ultrasound) | Controlled studies (RCTs, cohort studies, case–control studies) |
| MRI vs. no screening | Modeling/simulation studies that meet previously stated inclusion/exclusion criteria |
| Ipsilateral vs. contralateral detection | |
| MRI at various intervals | Observational studies (prospective and retrospective cohort studies, case–control studies, or cross-sectional studies) |
| Women with a personal history of breast cancer vs. women without | |
| Exclusion criteria | |
| Women with a personal history of breast cancer and a family history of breast cancer vs. no family history of breast cancer | Systematic reviews and/or meta-analyses |
| Non-research studies (e.g., editorials, letters) | |
| Outcomes | Other |
| Inclusion criteria | English language |
| Cancer detection rate (proportion of women with appositive screen result and a positive reference standard) | Peer-reviewed articles |
| Exclusion criteria | |
| Cancer detection rate for ipsilateral and contralateral breast cancer | Non-English language |
| PPV1 (malignancy rate among cases that test positive on screening) or false-positive rate | Abstracts only |