Table 4.
Cross-correlations between periostin levels and other measured factors. Overall cross-correlation of the analysed parameters and cross-correlation performed in particular study subpopulations of particular interest (conventional therapy/omalizumab/patients without CRSwNP/patients with CRSwNP, Spearman’s rho)
Age | Height | Weight | BMI | IgE [IU/ml] | ECP [μg/l] | AEC | eos % | FeNO [ppb] | FEV1 (l) | FEV1 (%pred) | OMA dose | Duration of OMA therapy | OMA cumulative dose | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Periostin [ng/ml] | Whole sample N = 48 | Spearman‘s rho | –0.178 | –0.027 | 0.051 | 0.147 | 0.243 | 0.167 | 0.280 | 0.192 | 0.159 | –0.117 | –0.166 | |||
Sig. (2-tailed) | 0.227 | 0.853 | 0.732 | 0.317 | 0.096 | 0.290 | 0.054 | 0.192 | 0.285 | 0.438 | 0.259 | |||||
Conventional therapy N = 38 | Spearman‘s rho | –0.235 | –0.057 | 0.060 | 0.206 | 0.364 | 0.103 | 0.207 | 0.121 | 0.151 | –0.129 | –0.178 | ||||
Sig. (2-tailed) | 0.155 | 0.732 | 0.720 | 0.215 | 0.025 | 0.575 | 0.214 | 0.468 | 0.373 | 0.446 | 0.286 | |||||
Omalizumab N = 10 | Spearman‘s rho | –0.195 | 0.301 | 0.152 | 0.103 | –0.115 | 0.455 | 0.382 | 0.515 | 0.522 | –0.233 | –0.055 | –0.070 | 0.176 | –0.036 | |
Sig. (2-tailed) | 0.589 | 0.398 | 0.676 | 0.777 | 0.751 | 0.187 | 0.276 | 0.128 | 0.122 | 0.546 | 0.881 | 0.848 | 0.627 | 0.920 | ||
Without CRSwNP N = 33 | Spearman‘s rho | –0.194 | 0.148 | 0.086 | 0.034 | 0.270 | 0.175 | 0.401 | 0.396 | 0.308 | –0.049 | –0.202 | ||||
Sig. (2-tailed) | 0.280 | 0.413 | 0.636 | 0.850 | 0.129 | 0.355 | 0.021 | 0.023 | 0.087 | 0.790 | 0.260 | |||||
With CRSwNP N = 15 | Spearman‘s rho | –0.447 | –0.667 | –0.368 | 0.246 | 0.321 | 0.028 | 0.091 | 0.029 | –0.349 | –0.055 | 0.172 | ||||
Sig. (2-tailed) | 0.095 | 0.007 | 0.177 | 0.376 | 0.243 | 0.931 | 0.747 | 0.919 | 0.203 | 0.852 | 0.541 |