Table 2.

Alkyne substrate scope.

Entry[a]	Alkyne R=	4	Yield [%][b]	ee [%]
1	Ph	4 a	98	97
2	p-MeOPh	4 b	63	96
3	p-CF3Ph	4 c	85	97
4	p-tolyl	4 d	83	96
5	p-ClPh	4 e	86	97
6	m-tolyl	4 f	82	97
7	o-tolyl	4 g	67	82
8[c]	TMS	4 h	86	95
9[d]	CH2OBn	4 i	85	85
10[e]	CH2CH2OBn	4 j	96	85
11	cyclopropyl	4 k	45	82
12	1-cyclohexenyl	4 l	50	71

^[a]See the Supporting Information for detailed procedures.

^[b]Isolated yields.

^[c]Ligand 5d was used.

^[d]Ligand 5e (R’=Ph, R″=Bn) was used.

^[e]Ligand 5 f (R′=2-naphthyl, R″=Bn) was used. (S)-Enantiomer was obtained.