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. 2020 May 25;11:806. doi: 10.3389/fmicb.2020.00806

TABLE 2.

Minimum inhibitory concentrations (MICs) and fractional inhibitory concentration indexes (FICIs) of EH and Colistin against 10 multidrug-resistant ExPEC isolates.

Strain no. MIC (mg/L) FICI Relationship

Colistin alone Ellipticine hydrochloride combination Colistin combination
E. coli (1145) 8 0.25 0.5 0.3125 S
E. coli (13712) 8 0.25 0.5 0.3125 S
E. coli (1209) 8 0.25 0.5 0.3125 S
E. coli (1341) 16 1 8 1.5 I
E. coli (1704087) 8 0.5 1 1.125 I
E. coli (42) 8 0.5 1 0.375 S
E. coli (148121) 16 0.25 4 0.5 S
E. coli (1411060) 8 0.25 1 0.375 S
E. coli (1603043) 8 0.25 2 0.5 S
E. coli (1604040) 4 0.25 0.5 0.25 S

S, synergy; I, indifference; A, antagonism.