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. 2020 May 5;11(6):1566–1577. doi: 10.1111/1759-7714.13430

Figure 7.

Figure 7

The antitumor activity of CM082 combined with gefitinib on H3255 tumor xenograft. (a) Images of the tumors after 21 days. (b) The tumor volumes of the mice. (c) The tumor growth inhibition rate of different drugs. (d) The bodyweights of the mice. (e) Immunohistochemistry was used to detect the proliferation marker Ki‐67, apoptotic cells (TUNEL method), endothelial marker CD31, and VEGF‐A. CM0821: 80 mg b.i.d., CM0822: 160 mg b.i.d. The data are expressed as mean ± standard deviation, **P < 0.01. Scale bar = 100 μm.