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. 2020 Apr 26;34(6):803–811. doi: 10.1177/0269215520911970

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Change from baseline to Week 4 and Week 12 in (a) upper limb CX_A, (b) lower limb CX_A, (c) upper limb active function, and (d) lower limb active function, during the open-label extension studies.

CX_A: composite active range of motion; MFS: Modified Frenchay Scale; n: number of patients with data at both Week 4 and Week 12 of each cycle.

Data are presented as mean [95% confidence interval]. Active function was assessed by the MFS (upper limb) and unaided comfortable barefoot walking speed (lower limb).