Table 3:
Mean scores on neuropsychometric testing.
| Dimensional measurements for all carriers | Deletion mean (SD); (range) SD shifta | Duplication Mean (SD); (range) SD shifta | Control mean (SD); (range); N | Statistic/significance |
| Verbal IQb | 95.5 (22.1) (70–95); 0.85 | 80.5 (31.1) (62–105)i; 1.85 | 108.3 (13.0) (77–128)i; N = 23 | F(2,56) = 7.6, P = 0.001, η2 = 0.21; Tukey, P = 0.001 |
| Nonverbal IQb | 96.2 (22.5) (71–84); 1.01 | 86.0 (32.1) (57–123)i; 1.69 | 111.4 (14.1) (89–140)i; N = 23 | F(2,56) = 6.1, P = 0.004, η2 = 0.18; Tukey, P = 0.003 |
| Overall adaptive compositec | 88.1 (21.2) (59–81) | 78.5 (19.3) (68–86) | N/A | F(1,32) = 1.9, P = 0.18, η2 = 0.05 |
| Purdue Pegboard both-hand T scored | 37.5 (13.9) (19–31); 0.65 | 26.2 (22.4) (9–51)i; 1.78 | 44.0 (7.5) (26–57)i; N = 18 | F(2,40) = 5.3, P = 0.009, η2 = 0.21; Tukey, P = 0.007 |
| Dimensional measurements for child carriers | Deletion Mean (SD); (Range) | Duplication Mean (SD); (Range) | Control Mean (SD); (Range) | Statistic/significance |
| ASD calibrated severity scoree | 2.3 (2.2) (1–6)i | 5.4 (2.5) (1–9)i | 1.0 (0.0) (1–1)i; N = 4 | F(2,16) = 6.8, P = 0.007, η2 = 0.46; Tukey, P = 0.01 |
| Nonword repetition standard scoref | 6.2 (3.0) (5–8); 0.37 | 6.4 (3.0) (7–8); 0.3 | 7.3 (1.1) (6–8); N = 4 | F(2,10) = 0.17, P = 0.8, η2 = 0.03 |
| Verbal IQb | 84.4 (24.6) (40–113); 1.0 | 73.8 (31.6) (24–119); 1.71 | 99.4 (12.5) (77–115); N = 8 | F(2,24) = 2.3, P = 0.12, η2 = 0.16 |
| Nonverbal IQb | 83.2 (24.2) (36–111); 1.52 | 80.1 (31.5) (17–123); 1.34 | 103.4 (10.8) (89–122); N = 8 | F(2,24) = 2.3, P = 0.12, η2 = 0.16 |
| Overall adaptive compositec | 75.1 (11.9) (59–91)i;1.56 | 78.4 (14.1) (60–98)i; 1.34 | 98.5 (7.0) (91–111)i; N = 8 | F(2,24) = 9.9, P = 0.001, η2 = 0.45; Tukey, P = 0.001 |
| Purdue Pegboard both-hand T scored | 23.7 (6.4) (19–31); 2.28 | 28.8 (15.3) (9–51); 1.78 | 46.5 (4.4) (44–52); N = 4 | F(2,8) = 3.4, P = 0.09, η2 = 0.46 |
| Movement ABC total standard Scoref,g | 7.2 (4.0) (2–12) | 4.2 (3.0) (1–9) | N/A | Unpaired t(8) = 1.3, P = 0.2 |
SD shift represents the standard deviation shift in observed performance in carriers from controls (in bold).
Verbal and nonverbal IQ scores have a mean of 100 and standard deviation of 15.
Overall adaptive composite score has a mean of 100 and standard deviation of 15.
Purdue T scores have a mean of 50 and standard deviation of 10.
Calibrated severity score ranges from 1–10; scores 1–3 are in the typical range. It is based on scoring on modules 1–3 of the Autism Diagnostic Observation Schedule (ADOS). As a result, adults (who completed ADOS module 4) are not included in the comparison.
Nonword repetition standard scores and Movement ABC Total Standard Scores have a mean of 10 and standard deviation of 3. These were only conducted with child participants.
Movement ABC conducted on subset of five deletion and five duplication child carriers.
Post hoc testing reveals significant difference between groups.