Figure 3.

CXCR3 Is Critical for Anti-Aspergillus Defense

(A) Kaplan-Meier survival of C57BL6 (n = 37) and Cxcr3^−/− (n = 35) mice challenged with 4–8 × 10⁷ CEA10 conidia. Data from three experiments were pooled.

(B–D) (B) Normalized lung fungal burden, (C) BALF LDH level, and (D) BALF albumin levels in C57BL6 and Cxcr3^−/− mice 48 h pi with 3 × 10⁷ CEA10 conidia. (A–D) Dots represent individual mice and data were pooled from 2–4 experiments and presented as mean ± SEM. Statistical analysis: Mann-Whitney test. See also Figure S3.