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. 2020 Apr 7;295(3):583–590. doi: 10.1148/radiol.2020191016

Figure 3e:

(a–c) Clear cell renal cell carcinoma (ccRCC) (arrow) in a 57-year-old man with Von Hippel–Lindau (VHL) disease that appears hypointense on (a) the baseline apparent diffusion coefficient (ADC) image (mean, 1536 × 10−6 mm2/sec) and shows 8.9 cm3 per year growth and 232-day doubling time between (b) baseline and (c) follow-up contrast-enhanced CT. (d–f) ccRCC (arrow) in a 61-year-old woman with VHL disease with a hyperintense appearance on (d) the baseline ADC image (mean, 2431 × 10−6 mm2/sec) with 2.5-cm3 per year growth and 1008-day doubling time between (e) baseline and (f) follow-up contrast-enhanced CT.

(a–c) Clear cell renal cell carcinoma (ccRCC) (arrow) in a 57-year-old man with Von Hippel–Lindau (VHL) disease that appears hypointense on (a) the baseline apparent diffusion coefficient (ADC) image (mean, 1536 × 10−6 mm2/sec) and shows 8.9 cm3 per year growth and 232-day doubling time between (b) baseline and (c) follow-up contrast-enhanced CT. (d–f) ccRCC (arrow) in a 61-year-old woman with VHL disease with a hyperintense appearance on (d) the baseline ADC image (mean, 2431 × 10−6 mm2/sec) with 2.5-cm3 per year growth and 1008-day doubling time between (e) baseline and (f) follow-up contrast-enhanced CT.