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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Obstet Gynecol. 2020 Jun;135(6):1281–1288. doi: 10.1097/AOG.0000000000003826

Table 3:

Responses of nulliparous women reporting use of alcohol, tobacco, and drugs during pregnancy

Characteristic In the 3 months
before
pregnancy
began
In the month
before visit 1
(first trimester
exposure)
In the month
before visit 2
(second
trimester
exposure)
In the month
before visit 3 (late
second/early third
trimester
exposure)
In the month
before the
delivery visit
(exposure around
the time of
delivery)
Alcohol
Drink alcoholic beverages 6477/10028 381/9824 531/9409 646/9217 434/7164
64.6% (63.6%-65.5%) 3.9% (3.5%-4.3%) 5.6% (5.2%-6.1%) 7.0% (6.5%-7.6%) 6.1% (5.5%-6.6%)
Drink > 1 day per week 2740/6459 33/378 14/528 45/641 48/431
42.4% (41.2%-43.6%) 8.7% (6.1%-12.0%) 2.7% (1.5%-4.4%) 7.0% (5.2%-9.3%) 11.1% (8.3%-14.5%)
Binge drinking 3414/6429 33/375 16/522 23/638 13/428
53.1% (51.9%-54.3%) 8.8% (6.1%-12.1%) 3.1% (1.8%-4.9%) 3.6% (2.3%-5.4%) 3.0% (1.6%-5.1%)
Tobacco
Smoke any tobacco products 1782/10028 592/10015 499/9407 432/9217 276/7162
17.8% (17.0%-18.5%) 5.9% (5.5%-6.4%) 5.3% (4.9%-5.8%) 4.7% (4.3%-5.1%) 3.9% (3.4%-4.3%)
Smoked >1 pack per day 257/1771 14/588 15/497 13/429 9/274
14.5% (12.9%-16.2%) 2.4% (1.3%-4.0%) 3.0% (1.7%-4.9%) 3.0% (1.6%-5.1%) 3.3% (1.5%-6.1%)
Exposed to second hand smoke 1901/5548 1452/5543 1377/5749 1263/6207 704/5308
34.3% (33.0%-35.5%) 26.2% (25.0%-27.4%) 24.0% (22.9%-25.1%) 20.4% (19.4%-21.4%) 13.3% (12.4%-14.2%)
Smoked ≥ 7 hours per week who exposed to second hand smoke 766/1901 512/1452 403/1377 397/1263 230/704
40.3% (38.1%-42.5%) 35.3% (32.8%-37.8%) 29.3% (26.9%-31.8%) 31.4% (28.9%-34.1%) 23.7% (29.2%-36.3%)
At least 1 person (excluding subject) who smoked in the home 855/5556 719/5553 683/5760 640/6210 373/5310
15.4% (14.5%-16.4%) 13.0% (12.1%-13.9%) 11.9% (11.0%-12.7%) 10.3% (9.6%-11.1%) 7.0% (6.4%-7.8%)
Drugs
Use any illegal drug or drug not prescribed for them 3425/10027* N/A 105/9407 63/9216 26/7163
34.2% (33.2%-35.1%) N/A 1.1 (0.9%-1.4%) 0.7% (0.5%-0.9%) 0.4% (0.2%-0.5%)
Use opioid (narcotics- heroin- methadone) 632/3425 N/A 5/105 2/63 5/26
18.5% (17.2%-19.8%) N/A 4.8% (1.6%-10.8%) 3.2% (0.4%-11.0%) 19.2% (6.6%-39.4%)
*

Have you EVER used illegal drugs or drugs not prescribed for you?

Compared to the first trimester- all p-values were < 0.001.

Compared to the second trimester- all p-values were < 0.001

Data are reported as n/N and % (95%CI) responding yes.

N/A= not asked at the visit