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. Author manuscript; available in PMC: 2021 Apr 2.
Published in final edited form as: Mol Cell. 2020 Feb 26;78(1):96–111.e6. doi: 10.1016/j.molcel.2020.02.006

Figure 6. Single-Chromosome Analysis Reveals Subpopulations with Unique Folding Patterns.

Figure 6.

(A) Power-law scaling of spatial distance to genomic distance for each cluster (blue, best fit curves of the raw data). s = scaling exponent of spatial distance, a = step size. Values in brackets are 95% confidence intervals of the fit. Dotted line represents the fractal globule model prediction with s = 1/3.

(B) Radial-normalized mean distance (RND) to nuclear boundary for each TAD in individual traces (see STAR Methods). Red dotted line indicates RND = 0.15 (lamina contact). Error bars represent ±SEM.