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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Am J Sports Med. 2018 Jan 24;46(4):890–899. doi: 10.1177/0363546517749834

TABLE 3.

Association of Magnetic Resonance Imaging Outcomes (T1ρ and T2) With Demographic and Cluster Characteristics Over All Time Pointsa

Predictor T1ρ, ms
T2, ms
Medial Femur Lateral Femur Medial Femur Lateral Femur
B (95% CI) P Value B (95% CI) P Value B (95% CI) P Value B (95% CI) P Value

Age 0.08 (0.02 to 0.13) .011 0.17 (0.08 to 0.26) <.001 0.07 (0.003 to 0.14) .041 0.15 (0.08 to 0.22) <.001
Sex b 2.90 (1.73 to 4.07) <.001 2.77 (1.38 to 4.16) <.001 3.10 (1.81 to 4.39) <.001 2.32 (1.06 to 3.59) <.001
BMI –0.33 (–0.53 to –0.13) .002 –0.17 (–0.44 to 0.11) .25 –0.26 (–0.42 to –0.10) .001 –0.19 (–0.41 to 0.03) .09
Meniscectomy c 0.19 (–1.60 to 1.98) .83 –0.62 (–2.75 to 1.51) .57 –0.58 (–1.91 to 0.75) .39 –0.82 (–2.55 to 0.90) .35
Marx 0.45 (0.23 to 0.68) <.001 0.30 (0.03 to 0.58) .031 0.27 (0.02 to 0.53) .038 0.24 (–0.01 to 0.49) .06
Allograft d 1.23 (–0.01 to 2.44) .051 1.22 (0.17 to 2.28) .023 0.83 (–0.28 to 1.95) .14 0.70 (–0.39 to 1.79) .21
Cluster e 1.36 (–0.06 to 2.80) .06 0.61 (–0.95 to 2.16) .44 0.30 (–1.02 to 1.63) .65 0.05 (–1.24 to 1.34) .94

Medial Tibia Lateral Tibia Medial Tibia Lateral Tibia

Age 0.10 (0.01 to 0.20) .034 0.09 (–0.08 to 0.26) .32 0.99 (0.01 to 0.19) .027 0.02 (–0.10 to 0.14) .71
Sex b 1.84 (0.18 to 3.51) .030 4.04 (2.26 to 5.81) <.001 1.79 (0.29 to 3.29) .02 3.44 (2.14 to 4.75) <.001
BMI –0.63 (–0.91 to –0.36) <.001 –0.01 (–0.28 to 0.27) .97 –0.44 (–0.70 to –0.18) .001 –0.02 (–0.20 to 0.16) .82
Meniscectomy c 3.04 (1.37 to 4.70) <.001 0.62 (–0.99 to 2.33) .45 2.24 (1.01 to 3.48) <.001 0.99 (–0.12 to 2.11) .08
Marx 0.59 (0.25 to 0.92) .001 0.26 (–0.26 to 0.77) .33 0.44 (0.17 to 0.71) .002 –0.01 (–0.35 to 0.36) .97
Allograft d 0.08 (–1.43 to 1.59) .92 1.05 (0.02 to 2.08) .045 0.62 (–0.54 to 1.79) .30 0.31 (–0.58 to 1.19) .50
Cluster e 3.29 (1.44 to 5.14) .001 –0.11 (–1.68 to 1.46) .89 1.48 (0.13 to 2.83) .032 –0.28 (–1.42 to 0.85) .62

Patella Trochlea Patella Trochlea

Age 0.20 (0.05 to 0.36) .012 0.14 (0.04 to 0.25) .007 0.07 (–0.05 to 0.19) .27 0.1 (0.03 to 0.18) .007
Sex b 4.17 (2.56 to 5.78) <.001 4.50 (3.29 to 5.72) <.001 3.96 (2.53 to 5.39) <.001 3.69 (2.51 to 4.87) <.001
BMI –0.26 (–0.52 to –0.01) .044 –0.15 (–0.42 to 0.12) .26 –0.11 (–0.31 to 0.09) .29 –0.15 (–0.34 to 0.04) .12
Meniscectomy c 0.13 (–2.15 to 2.42) .91 –0.88 (–2.71 to 0.95) .35 0.08 (–2.01 to 2.16) .94 –1.59 (–2.89 to –0.29) .017
Marx 0.64 (0.30 to 0.99) <.001 0.53 (0.28 to 0.79) <.001 0.40 (0.07 to 0.73) .019 0.38 (0.14 to 0.62) .002
Allograft d 0.98 (–0.20 to 2.17) .10 0.72 (–0.52 to 1.95) .26 0.94 (–0.20 to 2.08) .11 0.58 (–0.80 to 1.95) .41
Cluster e 2.46 (0.68 to 4.24) .007 1.09 (–0.35 to 2.53) .14 1.74 (0.11 to 3.36) .037 0.35 (–0.88 to 1.59) .58
a

Each entry indicates the increase in relaxation time (ms) for every unit increase of that factor. Bold indicates P < .05. BMI, body mass index.

b

A positive B value indicates that females have higher relaxation times.

c

A positive B value indicates higher relaxation times for those who had meniscectomy.

d

A positive B value indicates higher relaxation times for those with allograft versus those with autograft.

e

A positive B value indicates higher relaxation times in the high sulfated glycosaminoglycan group.