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. 2020 Mar 15;201(6):681–687. doi: 10.1164/rccm.201903-0623OC

Table 2.

Hazard Ratio (95% Confidence Interval) of Critical Illness Mortality per Admission Year Category Provided, with 2006–2008 Considered as Reference for All Analyses

  Admission Year
Multiplicative Interaction Term P Value
  2006–2008 2009–2010 2011–2012 2013–2014 2015–2016  
All hospitals Ref. 0.86 (0.84–0.89) 0.82 (0.80–0.84) 0.81 (0.79–0.82) 0.80 (0.78–0.82)
             
Minority-serving hospitals Ref. 0.83 (0.77–0.89) 0.88 (0.82–0.95) 0.79 (0.74–0.85) 0.88 (0.81–0.94) <0.001
Non–minority-serving hospitals Ref. 0.87 (0.85–0.89) 0.80 (0.79–0.82) 0.81 (0.79–0.82) 0.79 (0.77–0.81)  
             
Minority hospital defined as having greater than 25% African American or Hispanic census            
 Minority-serving hospitals Ref. 0.85 (0.80–0.90) 0.83 (0.78–0.87) 0.79 (0.75–0.83) 0.85 (0.80–0.90) 0.05
 Non–minority-serving hospitals Ref. 0.87 (0.84–0.89) 0.81 (0.79–0.83) 0.81 (0.79–0.83) 0.79 (0.77–0.81)  
GEE analysis in hospitals with >500 admissions to account for hospital correlation            
 Minority-serving hospitals Ref. 0.94 (0.92–0.95) 0.93 (0.91–0.95) 0.90 (0.88–0.93) 0.94 (0.91–0.97) 0.05
 Non–minority-serving hospitals Ref. 0.94 (0.92–0.95) 0.90 (0.88–0.92) 0.89 (0.87–0.91) 0.88 (0.86–0.90)  
Cox regression in hospitals with participation in four consecutive time periods            
 Minority-serving hospitals Ref. 0.82 (0.76–0.88) 0.87 (0.81–0.94) 0.75 (0.70–0.81) 0.87 (0.81–0.94) 0.003
 Non–minority-serving hospitals Ref. 0.87 (0.85–0.89) 0.81 (0.79–0.83) 0.82 (0.80–0.84) 0.80 (0.77–0.82)  

Definition of abbreviations: GEE = generalized estimating equation; Ref. = reference.

Adjusted hazard ratios for critical illness mortality according to admission year and hospital minority composition. Adjusted for age, sex, ethnicity, unit type, admission diagnosis, Charlson comorbidity score, and illness severity. In addition, alternative definition of hospital minority composition, and analytic approaches to account for within hospital correlation and hospital participation, are provided. Multiplicative interaction P value between indicator for minority-serving hospitals and admission year (defined continuously) provided.