Table 1.
Summary of Observations from Mice Exposed to Viable Stachybotrys chartarum
Arterial Remodeling |
Airway Changes |
Alveolar Changes |
||||||
---|---|---|---|---|---|---|---|---|
Early | Continuum | Advanced | Thrombi | Inflammation | Mucous Metaplasia | Histiocytosis | M2 Histiocytosis | |
4 wk | ||||||||
Strain A | 0/6 | 3/6 | 2/6 | 4/6 | 5/6 | 5/6 | 5/6 | 0/6 |
Strain B | 3/6 | 2/6 | 0/6 | 0/6 | 4/6 | 0/6 | 0/6 | 0/6 |
13 wk | ||||||||
Strain A | 0/6 | 0/6 | 6/6 | 2/6 | 6/6 | 6/6 | 1/6 | 5/6 |
Strain B | 0/6 | 1/6 | 5/6 | 2/6 | 5/6 | 5/6 | 2/6 | 4/6 |
Lungs (n = 3/group) from 24- and 48-hour time points were pooled together for n = 6.