Table 6.
Altered MicroRNAs after Exposure
| miRNAs | Strain A |
Strain B |
Strain A |
Strain B |
||||
|---|---|---|---|---|---|---|---|---|
| 4 wk |
13 wk |
4 wk |
13 wk |
4 wk |
13 wk |
4 wk |
13 wk |
|
| 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | |
| Viable | ||||||||
| mmu-miR-133a-3p | −3.2* | −3.0* | −3.3* | −2.4* | — | — | — | −2.3 |
| mmu-miR-144-5p | −2.2* | −2.1* | −2.2* | −3.0* | — | — | — | — |
| mmu-miR-181b-5p | −2.2* | −2.1* | — | — | — | — | — | — |
| mmu-miR-21a-5p | — | — | 2.9* | 1.9* | — | — | — | — |
| mmu-miR-23b-3p | −3.4* | −2.3* | — | −2.1* | — | — | −2.0* | — |
| mmu-miR-335-5p | −2.2* | −2.7* | — | −2.3 | — | — | — | — |
| mmu-miR-339-5p | −2.0* | −2.9* | −2.0* | −2.4* | — | — | — | — |
| mmu-miR-365-3p | −2.2* | −2.4* | — | −1.7* | — | — | — | — |
| mmu-miR-374b-5p | −2.2* | −2.3* | — | −2.0* | — | — | — | −1.8* |
| mmu-miR-491-3p | — | 3.0* | — | 2.2* | — | — | −1.7* | — |
| mmu-miR-669d-5p | 2.7* | 2.8* | — | 2.0* | — | — | — | — |
| mmu-miR-706 | 4.7* | 7.4* | 2.2* | 3.2* | — | — | — | 2.1* |
| HIC | ||||||||
| mmu-miR-133a-3p | −4.2* | −3.4* | −5.9* | −3.2* | — | 2.1 | — | — |
| mmu-miR-144-5p | — | — | −4.4* | −2.3* | — | — | — | — |
| mmu-miR-181b-5p | −2.7* | −2.4* | −3.1* | −2.2* | — | — | — | — |
| mmu-miR-21a-5p | — | — | −3.1* | — | — | — | — | — |
| mmu-miR-23b-3p | −1.9* | — | — | — | — | — | — | — |
| mmu-miR-335-5p | −2.8* | −2.3* | −3.0* | −2.3* | — | — | — | — |
| mmu-miR-339-5p | −2.2* | −2.4* | −3.3* | −2.5* | — | — | — | — |
| mmu-miR-365-3p | −4.3* | −3.6* | −4.6* | −3.2* | — | — | — | — |
| mmu-miR-374b-5p | −2.3* | −2.0* | −3.3* | −2.1* | — | — | — | — |
| mmu-miR-491-3p | 2.7* | 5.9* | 3.3* | 3.9* | — | — | — | — |
| mmu-miR-669d-5p | 3.6* | 3.1* | 3.9* | 2.4* | — | — | — | — |
| mmu-miR-706 | 7.4* | 7.5* | 6.3* | 3.7* | — | — | — | — |
Definition of abbreviations: miR and miRNA = microRNA.
Values are reported as fold change between the exposed group compared with air-only control group. Dashes indicate miRNA was unaltered.
*
P ≤ 0.05; n = 5.