Comparison 2. H. pylori eradication vs control ‐ subgroup analysis according to presence or absence of pre‐neoplastic lesions at baseline.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Incidence of gastric cancer according to presence or absence of pre‐neoplastic lesions at baseline	6	6481	Risk Ratio (M‐H, Random, 95% CI)	0.72 [0.45, 1.17]
1.1 Patients with precancerous lesions	4	3425	Risk Ratio (M‐H, Random, 95% CI)	0.86 [0.47, 1.59]
1.2 Patients with out precancerous lesions	2	1812	Risk Ratio (M‐H, Random, 95% CI)	0.42 [0.02, 7.69]
1.3 Mixed patients with and without precancerous lesions or ulcer (can't separate)	2	1244	Risk Ratio (M‐H, Random, 95% CI)	0.38 [0.12, 1.23]