Date	Event	Description
18 December 2013	New citation required but conclusions have not changed	The conclusions of the review have not changed. Characteristics and effects of interventions to improve medication adherence varied among studies, with only 5 of the 17 highest quality trials providing convincing evidence for improvement. Current methods of improving adherence for chronic health problems are mostly complex and not very effective, so that the full benefits of treatment cannot be realized.
18 December 2013	New search has been performed	We added 15 new authors in addition to RB Haynes, who was an author on the previous version of the review. The research objectives and inclusion criteria remain the same as in the previous review. We added the assessment of the risk of bias to the outcome measures. We updated the search filters for detecting relevant studies. We added 109 new studies in this 2013 update from searches run in January 2013.