4. Sensitivity analysis ‐ quality.

Outcome	All studies	Higher quality studies
6‐month survival	NSSD	NSSD
12‐month survival	NSSD	NSSD
24‐month survival	NSSD	NSSD
Overall response	NSSD	P
Complete response	P	P
Toxic death	NSSD	NSSD
Nausea and Vomiting	NP	NP
Alopecia	NSSD	NP
Infection	NSSD	P
Anaemia	NSSD	NSSD
Leukopenia	NSSD	P
Thrombocytopenia	NP	NSSD
Granulocytopenia	NSSD	NSSD

NSSD ‐ No statistically significant difference between treatment groups.

P ‐ Statistically significant effect favouring platinum‐based regimens.

NP ‐ Statistically significant effect favouring non‐platinum‐based regimens.