Table 2.
Patient Demographics and Predictors of Surgical Resection, Radiotherapy, and Chemotherapy Within 6 Months of Diagnosis
| Surgical Resection | Radiotherapy | Chemotherapy | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Level | No.(%) Total | No.(%) Treated | Adjusted OR* (95% CI) | P | No.(%) Treated | Adjusted OR* (95% CI) | P | No.(%) Treated | Adjusted OR* (95% CI) | P |
| Histology | Astrocytoma | 891 (83.5) | 478 (53.6) | 1 (reference) | .06 | 596 (66.9) | 1 (reference) | .90 | 103 (11.6) | 1 (reference) | .01 |
| Oligodendroglioma | 176 (16.5) | 101 (57.4) | 1.41 (0.99–2.02) | 108 (61.4) | 0.98 (0.67–1.42) | 34 (19.3) | 1.86 (1.16–3.01) | ||||
| Grade | Low | 180 (16.9) | 94 (52.2) | 1 (reference) | <.0001 | 102 (56.7) | 1 (reference) | <.0001 | 11 (6.1) | 1 (reference) | .002 |
| Anaplastic | 723 (67.8) | 425 (58.8) | 1.33 (0.94–1.86) | 536 (74.1) | 2.32 (1.62–3.31) | 108 (14.9) | 3.25 (1.65–6.38) | ||||
| Unknown | 164 (15.4) | 60 (36.6) | 0.53 (0.34–0.83) | 66 (40.2) | 0.57 (0.36–0.90) | 18 (11.0) | 1.93 (0.85–4.39) | ||||
| Age at diagnosis, y | 65–69 | 292 (27.4) | 172 (58.9) | 1 (reference) | .0003 | 222 (76.0) | 1 (reference) | <.0001 | 64 (21.9) | 1 (reference) | <.0001 |
| 70–74 | 288 (27.0) | 177 (61.5) | 1.09 (0.77–1.53) | 196 (68.1) | 0.61 (0.41–0.89) | 36 (12.5) | 0.50 (0.31–0.80) | ||||
| 75–79 | 280 (26.2) | 145 (51.8) | 0.75 (0.54–1.06) | 178 (63.6) | 0.52 (0.35–0.77) | 26 (9.3) | 0.37 (0.22–0.61) | ||||
| 80–84 | 132 (12.4) | 61 (46.2) | 0.62 (0.40–0.95) | 72 (54.5) | 0.39 (0.24–0.62) | 7 (5.3) | 0.18 (0.08–0.43) | ||||
| ≥85 | 75 (7.0) | 24 (32.0) | 0.36 (0.21–0.62) | 36 (48.0) | 0.33 (0.19–0.58) | <5 | 0.20 (0.07–0.60) | ||||
| Gender | Male | 525 (49.2) | 290 (55.2) | 1 (reference) | .98 | 343 (65.3) | 1 (reference) | .06 | 85 (16.2) | 1 (reference) | .008 |
| Female | 542 (50.8) | 289 (53.3) | 1.00 (0.76–1.30) | 361 (66.6) | 1.32 (0.99–1.77) | 52 (9.6) | 0.58 (0.39–0.87) | ||||
| Marital status | Married | 663 (62.1) | 376 (56.7) | 1 (reference) | .74 | 467 (70.4) | 1 (reference) | .004 | 103 (15.5) | 1 (reference) | .45 |
| Unmarried | 362 (33.9) | 181 (50.0) | 0.89 (0.66–1.19) | 215 (59.4) | 0.61 (0.45–0.84) | 29 (8.0) | 0.74 (0.46–1.19) | ||||
| Unknown | 42 (3.9) | 22 (52.4) | 0.96 (0.50–1.83) | 22 (52.4) | 0.53 (0.27–1.03) | 5 (11.9) | 0.95 (0.34–2.66) | ||||
| Race | White | 966 (90.5) | 530 (54.9) | 1 (reference) | .32 | 642 (66.5) | 1 (reference) | .22 | 131 (13.6) | 1 (reference) | .10 |
| Black | 35 (3.3) | 16 (45.7) | 0.64 (0.31–1.32) | 21 (60.0) | 0.65 (0.30–1.40) | <5 | 0.65 (0.34–2.66) | ||||
| Other | 66 (6.2) | 33 (50.0) | 0.77 (0.46–1.29) | 41 (62.1) | 0.67 (0.39–1.16) | <5 | 0.28 (0.18–2.28) | ||||
| Year of diagnosis | 1994–1996 | 312 (29.2) | 163 (52.2) | 1 (reference) | .63 | 212 (67.9) | 1 (reference) | .29 | 42 (13.5) | 1 (reference) | .46 |
| 1997–1999 | 283 (26.5) | 162 (57.2) | 1.17 (0.84–1.64) | 200 (70.7) | 1.00 (0.68–1.45) | 44 (15.5) | 1.10 (0.67–1.79) | ||||
| 2000–2002 | 472 (44.2) | 254 (53.8) | 1.12 (0.83–1.51) | 292 (61.9) | 0.80 (0.58–1.11) | 51 (10.8) | 0.83 (0.52–1.31) | ||||
| Census tract Poverty level | <10% | 674 (63.2) | 363 (53.9) | 1 (reference) | .33 | 442 (65.6) | 1 (reference) | .49 | 87 (12.9) | 1 (reference) | .004 |
| ≥10% | 359 (33.7) | 195 (54.3) | 1.15 (0.87–1.53) | 240 (66.9) | 1.20 (0.88–1.64) | 39 (10.9) | 0.95 (0.61–1.48) | ||||
| Unknown | 34 (3.2) | 21 (61.8) | 1.65 (0.74–3.67) | 22 (64.7) | 1.16 (0.50–2.66) | 11 (32.4) | 4.73 (1.86–12.0) | ||||
| Urban/rural | Big metropolitan or metropolitan | 913 (85.6) | 502 (55.0) | 1 (reference) | .06 | 602 (65.9) | 1 (reference) | .37 | 119 (13.0) | 1 (reference) | .28 |
| Urban, less urban, or rural | 154 (14.4) | 77 (50.0) | 0.70 (0.49–1.01) | 102 (66.2) | 0.83 (0.56–1.24) | 18 (11.7) | 0.73 (0.41–1.30) | ||||
| No. of prior cancers | 0 | 915 (85.8) | 497 (54.3) | 1 (reference) | .82 | 607 (66.3) | 1 (reference) | .72 | 111 (12.1) | 1 (reference) | .15 |
| 1 | 129 (12.1) | 69 (53.5) | 0.88 (0.58–1.32) | 83 (64.3) | 0.89 (0.57–1.39) | 24 (18.6) | 1.26 (0.71–2.24) | ||||
| ≥2 | 23 (2.2) | 13 (56.5) | 0.94 (0.37–2.36) | 14 (60.9) | 0.71 (0.27–1.86) | <5 | 0.26 (0.05–1.33) | ||||
| Comorbidity index | 0 | 790 (74.0) | 442 (55.9) | 1 (reference) | .17 | 540 (68.4) | 1 (reference) | .41 | 113 (14.3) | 1 (reference) | .52 |
| 1 | 177 (16.6) | 94 (53.1) | 0.97 (0.68–1.37) | 107 (60.5) | 0.82 (0.57–1.18) | 16 (9.0) | 0.74 (0.41–1.33) | ||||
| ≥2 | 100 (9.4) | 43 (43.0) | 0.66 (0.42–1.02) | 57 (57.0) | 0.79 (0.50–1.25) | 8 (8.0) | 0.78 (0.35–1.72) | ||||
OR indicates odds ratio; 95% CI, 95% confidence interval.
*
Based on a multivariate logistic regression model in which each variable was adjusted for all others.