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. 2020 May 20;128(5):057001. doi: 10.1289/EHP6301

Figure 7.

Figures 7A to 7E are stream graphs with Figures 7A and 7C to 7E plotting number of quantities ranging from 0 to 30 in increments of 5, and Figure B plotting number of quantities ranging from 0 to 25 in increments of 5 (y-axis) across Original and permuted data labeled 25 to 250 BPA, Veh to 2.5 BPA, 2.5 to 25 BPA, 250 to 2500 BPA, and 2500 to 25000 BPA, respectively, (x-axis) for PND90SD, PND90CD, 6MSD, and 6MCD.

Number of quantities that have their largest difference between the target consecutive concentration (A) 25–250BPA and the other consecutive concentrations [(B) Veh–2.5BPA; (C) 2.5–25BPA; (D) 250–2500BPA, and (E) 2500–25000BPA] for the data sets PND90SD, PND90CD, 6MSD, and 6MCD. Units: μg/kg body weight (BW) per day. In each graph: left, original data, right 20 data sets obtained by random permutation of the condition of each animal. The sum of these quantities (gray horizontal line) is higher with the original data set than with each one of the 20 permuted data sets. Note: BPA, bisphenol A; CD, continuous-dose; Control, vehicle control; M, month; PND, postnatal day; SD, stop-dose.