Table 3.
Stability data for carfentanil and norcarfentanil in extracted samples stored at 10 °C and in plasma stored at −80 °C.
| Analyte | Nominal Conc. (pg/mL) |
Stability (%) a | ||||||
|---|---|---|---|---|---|---|---|---|
| Extracted samples stored at 10 °C |
Plasma samples stored at −80 °C |
|||||||
| 24 h | 48 h | 24 h | 1 month | 2 months | 2 freeze-thaw cycles | |||
| Carfentanil | 25 | 7.9 (2.8) | −7.7 (7.1) | 6.3 (6.1) | −7.2 (5.3) | −3.4 (1.9) | 0.7 (6.7) | |
| 4008 | −8.8 (3.2) | −9.9 (3.4) | −14 (4.3) | −20 (5.8) | −18 (10) | 8.2 (3.7) | ||
| Norcarfentanil | 25 | 1.7 (8.2) | 11 (5.1) | 8.7 (11) | −5.8 (7.0) | −4.9 (3.0) | −3.0 (9.3) | |
| 4008 | −4.6 (1.0) | 1.1 (3.1) | −8.2 (3.2) | −13 (2.1) | −16 (11) | 5.0 (1.5) | ||
a
% CV in parentheses