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[Preprint]. 2020 May 21:2020.05.21.108381. [Version 1] doi: 10.1101/2020.05.21.108381

Fig. 7. Handheld point of care instrument and additively manufactured cartridge.

Fig. 7.

(a) Schematic of the handheld point of care instrument showing components in an exploded view. A smartphone images the cartridge, while isothermal heating and illumination are battery powered. Optical components integrated with the instrument match the excitation and emission characteristics of the fluorescent signal. (b) Photograph of the instrument used for rapid detection. (c) Diagram of the diagnostic cartridge used for rapid detection of SARS-CoV- 2 in VTM. Two inlets mate with syringes that inject either RT-Lamp Reagents or Thermally Lysed Patient Sample into a 3D serpentine mixing region before filling the amplification and diagnostic region. Device dimensions are highlighted for the 3D mixer and amplification and diagnostic region.