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SARS-CoV-2 induced CPE in (A) Vero E6 and (B) ACE2-expressing A549 cells in the presence of bepridil
| A. | ||
|---|---|---|
| Bepridil (μM) | Repeat 1 | Repeat 2 |
| 200 | Ca | C |
| 100 | C | C |
| 50 | C | C |
| 20 | NDb | ND |
| 10 | ND | ND |
| 5 | ND | ND |
| 2.5 | CPE | CPE |
| 1.25 | CPE | CPE |
| 0.62 | CPE | CPE |
| 0.31 | CPE | CPE |
| 0.16 | CPE | CPE |
| B. | ||
| Bepridil (μM) | Repeat 1 | Repeat 2 |
| 200 | ND | ND |
| 100 | ND | ND |
| 50 | ND | ND |
| 25 | ND | ND |
| 12.5 | ND | ND |
| 6.25 | ND | ND |
| 3.12 | CPE | CPE |
| 1.56 | CPE | CPE |
Cytotoxicity;
Both cytotoxicity and CPE are not detected.
