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. 2020 Jun 1;15(6):e0234181. doi: 10.1371/journal.pone.0234181

Table 2. ROC curve comparison between the different prognostic scores.

Test Area p 95% CI Cut-off Sensitivity (%) Specificity (%)
In-Hospital mortality
APACHE II 0.836 <0.001 0.75–0.921 22 82.6 68
APACHE III 0.818 <0.001 0.736–0.899 81 78.5 64
APACHE IV 0.792 <0.001 0.705–0.878 74 76 64
SAPS II 0.818 <0.001 0.73–0.905 48 78.5 64
SAPS III 0.809 <0.001 0.712–0.905 71 75.2 80
SOFA 0.890 <0.001 0.835–0.943 6 85.1 76
MPM II Day 0 mortality 0.803 <0.001 0.719–0.886 35% 79.3 76
MPM III Day 0 mortality 0.794 <0.001 0.701–0.885 35% 80.2 76
90-day mortality
APACHE II 0.879 <0.001 0.798–0.959 21 86.4 76.2
APACHE III 0.876 <0.001 0.805–0.945 81 79.2 76.2
APACHE IV 0.856 <0.001 0.779–0.933 74 76.8 76.2
SAPS II 0.854 <0.001 0.764–0.943 50 74.4 81
SAPS III 0.888 <0.001 0.82–0.955 70 77.6 90.5
SOFA 0.905 <0.001 0.85–0.959 6 84.8 85.7
MPM II Day 0 mortality 0.854 <0.001 0.78–0.926 34% 81.6 85.7
MPM III Day 0 mortality 0.848 <0.001 0.774–0.921 34% 80.8 85.7

Cut-off values were derived based on the ROC graphs (Figs 2 and 3). CI: Confidence interval, APACHE: Acute Physiology Assessment and Chronic Health Evaluation, SAPS: Simplified Acute Physiology Score, SOFA: Sequential Organ Failure Assessment, MPM: Mortality Prediction Model.