Table 2. Result of structural similarity search using the Dali server.

PDB IDa	Z score	RMSD (Å)	LALIb	Identity (%)	Protein namec	Organism	Activity	Family	Referenced
5mqr (A)	31.4	2.6	459	19	BT_1020	Bacteroides thetaiotaomicron	β-L-Arabinofuranosidase	GH142	[8]
5ca4 (A)	21.4	4.6	547	11	YgjK	Escherichia coli	α-Glycosidase	GH63	[30]
2z07 (A)	20.4	2.9	315	9	TTHA0978	Thermus thermophilus	(Uncharacterized)	GH63	TBP
3cih (A)	20.3	4.3	441	10	BT_1001	Bacteroides thetaiotaomicron	α-L-Rhamnosidase	GH78	[8]
3w5m (A)	19.4	3.8	427	13	SaRha78A	Streptomyces avermitilis	α-L-Rhamnosidase	GH78	[31]
1v7v (A)	19.4	4.2	581	9	ChBP	Vibrio proteolyticus	Chitobiose phosphorylase	GH94	[32]
4wvb (A)	19.0	2.9	315	9	Tt8MGH	Thermus thermophilus	Mannosylglycerate hydrolase	GH63	[33]
6gsz (A)	19.0	3.5	395	14	α-Rha	Aspergillus terreus	α-L-Rhamnosidase	GH78	[34]
2jjb (B)	19.0	3.4	341	12	Tre37A	Escherichia coli	α,α-Trehalase	GH37	[35]
5ohz (C)	18.7	3.7	331	8	MhGgH	Mycolicibacterium hassiacum	Glucosylglycerate hydrolase	GH63	[36]
4zlf (A)	18.1	4.5	469	10	CBAP	Saccharophagus degradans	Cellobionic acid phosphorylase	GH94	[37]
3qde (A)	18.1	4.2	585	10	CtCBP	Clostridium thermocellum	Cellobiose phosphorylase	GH94	[38]
3afj (A)	18.1	4.2	584	11	CgCBP	Cellvibrio gilvus	Cellobiose phosphorylase	GH94	[39]
4j5t (A)	18.0	3.7	444	9	GluI	Saccharomyces cerevisiae	Processing α-glucosidase I	GH63	[40]

The whole HypBA2 structure including all domains were used.

^aChain ID is shown in parentheses.

^bNumber of aligned residues.

^cTTHA0978 and Tt8MGH are the identical protein.

^dTBP: to be published.