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. 2020 Jun 1;15(6):e0233949. doi: 10.1371/journal.pone.0233949

Table 2. Association of birth weight, feeding history and history of comorbidities as risk factors for global developmental delay (cognitive, language and motor) in 100 children of severe acute malnutrition in Ujjain, India.

Global developmental delay
Independent variable Total n = 100 Yes n = 58 (58%a) No n = 42 (42%b) OR 95% CI P value
Low birth weight No 64(64) 24(37) 40(63) Reference Reference -
Yes 36(36) 34(94) 2(6) 28.3 6.3 to 28.7 <0.001
Exclusive breastfeeding No 22(22) 19(86) 3(14) Reference Reference -
Yes 78(78) 39(50) 39(50) 6.3 1.7 to 23.1 0.005
Bottle feeding No 17(17) 14(82) 3(18) Reference Reference -
Yes 83(83) 44(53) 39(47) 0.24 0.06 to 0.90 0.035
Initiation of CF (at 6 months) No 55(55) 39(71) 16(29) Reference Reference -
Yes 45(45) 19(42) 26(58) 0.29 0.13 to 0.68 0.004
≤3 feeds per day No 59(59) 43(73) 16(27) Reference Reference -
Yes 41(41) 15(37) 26(63) 0.21 0.09 to 0.50 <0.001
H/o diarrhea (in last one month) No 58(58) 24(41) 34(59) Reference Reference -
Yes 42(42) 34(81) 8(19) 6.02 2.37 to 15.27 <0.001
H/o of pneumonia (in last one month) No 86(86) 46(53) 40(47) Reference Reference -
Yes 14(14) 12(86) 2(14) 5.21 1.10 to 24.72 0.037

%a Column percentage

%b Row percentage, LBW low birth weight

†- CF complimentary feeding; H/o History of; OR Odds ratios; CI confidence intervals.