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. 2020 Jun 1;15(6):e0233894. doi: 10.1371/journal.pone.0233894

Table 2. Baseline and procedural characteristics of patients (number of included studies = 27).

BEV (Edwards) SEV (Medtronic)
Variable Available data, n Weighted % or mean ± SD Available data, n Weighted % or mean ± SD
Age (year) 1087 78.0 ± 1.6 788 75.6 ± 10.0
Male (%) 1097 63.3% 751 55.3%
Log EuroSCORE 730 21.7 ± 9.9 586 26.2 ± 3.4
EuroSCORE II 53 19.6 ± 5.7 188 11.3 ± 2.9
STS score 1087 9.0 ± 2.5 678 9.2 ± 2.2
CAD (%) 491 65.2% 431 61.7%
Prior stroke (%) 1065 13.7% 666 11.7%
Prior Afib (%) 392 46.2% 467 42.0%
Prior PPM (%) 943 17.2% 377 22.5%
PAD (%) 1050 23.7% 674 22.7%
CKD (%) 1009 37.4% 674 34.3%
AR ≥moderate (%) 648 43.4% 509 54.0%
Bioprosthesis age (year) 732 10.5 ± 1.6 657 9.9 ± 1.3
Stented valve (%) 1078 84.2% 867 75.1%
Stentless valve (%) 809 13.6% 867 19.6%
Bioprosthesis size (%) 1097 746
    ≤21 mm 25.6% 30.7%
    21–24.9 mm 40.4% 37.9%
    ≥25 mm 31.4% 28.9%
    Unknown 2.3% 3.2%
Mode of failure (%)
    AS 1126 45.8% 632 53.2%
    AR 1126 28.0% 620 27.3%
    Mix 1116 26.6% 583 21.8%
LVEF (%) 829 50.0 ± 2.7 527 51.1 ± 3.0
AV area (cm2) 699 0.90 ± 0.08 671 0.95 ± 0.09
AVA index (cm2/m2) 900 0.53 ± 0.06 213 0.55
Max PG (mmHg) 341 62.6 ± 8.5 423 61.0 ± 9.2
Mean PG (mmHg) 1022 34.6 ± 3.8 754 36.0 ± 4.4
Fluoroscopic time (min) 436 18.3 ± 3.4 92 19.6 ± 9.8
THV size ≤23 mm (%) 1299 67.5% 490 26.9%
TF access (%) 1076 68.5% 561 95.0%

Abbreviations: Afib, atrial fibrillation; AR, aortic regurgitation; AS, aortic stenosis; AV, aortic valve; AVA, aortic valve area; CAD, coronary artery disease; CKD, chronic kidney disease; LVEF, left ventricular ejection fraction; PAD, peripheral artery disease; PG, pressure gradient; PPM, permanent pacemaker; PVL, paravalvular leak; STS, Society of Thoracic Surgery; TF, transfemoral; THV, transcatheter heart valve.