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. 2020 May 22;11(5):e00179. doi: 10.14309/ctg.0000000000000179

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© 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 3. — FGFR4 IHC predicts treatment outcomes. (a) Representative images of graded FGFR4 protein expression by IHC (×400 magnification; scale bar = 50 μm). (b) Median progression-free survival (PFS) rates for low, moderate, and high FGFR4 expression were 2.5, 5.3, and 6.5 months, respectively. (c) PFS for FGFR4-IHC negative (low) and positive (moderate and high). (d) Tumor objective response in mRECIST according to FGFR4-IHC. FGFR, fibroblast growth factor receptor; IHC, immunohistochemistry; mRECIST, modified Response Evaluation Criteria in Solid Tumor; PD, progression of disease; PR, partial response; SD, stable disease.